UniProt P74334
Apocarotenoid-15,15'-oxygenase (P74334)
Apocarotenoid-15,15'-oxygenase (UniProt P74334), EC 1.13.11.75: 22 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P74334
- Protein
- Apocarotenoid-15,15'-oxygenase
- EC
- 1.13.11.75
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 80 · 4 records with a druggable one
Structures
23 records of P74334 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BIW | Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, native enzyme | x-ray diffraction | A, B, C, D | — | — |
| 2BIW | Crystal structure of apocarotenoid cleavage oxygenase from synechocystis, native enzyme | x-ray diffraction | A, B, C, D | — | — |
| 2BIX | Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, Fe-free apoenzyme | x-ray diffraction | A, B | — | — |
| 2BIX | Crystal structure of apocarotenoid cleavage oxygenase from synechocystis, fe-free apoenzyme | x-ray diffraction | A, B | — | — |
| 4OU8 | Crystal structure of apocarotenoid oxygenase in the presence of C8E6 | x-ray diffraction | A, B, C, D | — | — |
| 4OU9 | Crystal structure of apocarotenoid oxygenase in the presence of Triton X-100 | x-ray diffraction | A, B, C, D | — | — |
| 4OU9 | Crystal structure of apocarotenoid oxygenase in the presence of triton X-100 | x-ray diffraction | A, B, C, D | — | — |
| 5KJA | Synechocystis apocarotenoid oxygenase (ACO) mutant - Trp149Ala | x-ray diffraction | A, B, C, D, E | CL, FE2 | 20 (best 0.87) |
| 5KJA | Synechocystis apocarotenoid oxygenase (aco) mutant - TRP149ALA | x-ray diffraction | A, B, C, D, E | CL, FE2 | — |
| 5KJB | Synechocystis apocarotenoid oxygenase (ACO) mutant - Glu150Asp | x-ray diffraction | A, B, C, D, E | FE2 | 20 (best 0.87) |
| 5KJB | Synechocystis apocarotenoid oxygenase (aco) mutant - GLU150ASP | x-ray diffraction | A, B, C, D, E | FE2 | — |
| 5KJD | Synechocystis apocarotenoid oxygenase (ACO) mutant - Glu150Gln | x-ray diffraction | A, B, C, D, E | FE2 | 20 (best 0.87) |
| 5KJD | Synechocystis apocarotenoid oxygenase (aco) mutant - GLU150GLN | x-ray diffraction | A, B, C, D, E | FE2 | — |
| 5KK0 | Synechocystis ACO mutant - T136A | x-ray diffraction | A, B, C, D | FE2, CL | — |
| 5KK0 | Synechocystis aco mutant - T136A | x-ray diffraction | A, B, C, D | FE2, CL | — |
| 6BIG | Crystal structure of cobalt-substituted Synechocystis ACO | x-ray diffraction | A, B, C, D | CO, CL | 20 (best 0.87) |
| 6BIG | Crystal structure of cobalt-substituted synechocystis aco | x-ray diffraction | A, B, C, D | CO, CL | — |
| 6C7K | Crystal structure of an ACO/RPE65 chimera | x-ray diffraction | A, B, C, D | FE2, CL | — |
| 6C7K | Crystal structure of an ACO/RPE65 chimera | x-ray diffraction | A, B, C, D | FE2, CL | — |
| 6C7O | Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form | x-ray diffraction | A, B | FE2 | — |
| 6C7O | Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form | x-ray diffraction | A, B | FE2 | — |
| 6C7P | Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form | x-ray diffraction | B, A | FE2 | — |
| P74334 | AlphaFold monomer V2.0 prediction for apocarotenoid-15,15'-oxygenase (P74334) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5KJA chain A against the predicted model P74334: TM-score 1.00, RMSD 0.25 Å
- 5KJA chain A against the predicted model P74334: TM-score 1.00, RMSD 0.25 Å
- 5KJA chain B against the predicted model P74334: TM-score 1.00, RMSD 0.26 Å
- 5KJA chain B against the predicted model P74334: TM-score 1.00, RMSD 0.26 Å
- 5KJD chain A against the predicted model P74334: TM-score 1.00, RMSD 0.27 Å
- 5KJD chain A against the predicted model P74334: TM-score 1.00, RMSD 0.27 Å
- 5KJA chain E against the predicted model P74334: TM-score 1.00, RMSD 0.28 Å
- 5KJA chain E against the predicted model P74334: TM-score 1.00, RMSD 0.28 Å
- 5KJB chain A against the predicted model P74334: TM-score 1.00, RMSD 0.29 Å
- 5KJB chain A against the predicted model P74334: TM-score 1.00, RMSD 0.29 Å
Elsewhere
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