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Sequential reorganization of beta-sheet topology by insertion of a single strand

Analyse Sequential reorganization of beta-sheet topology by insertion of a single strand in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2B7X
Type: protein
Length: 631 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysozyme
EC: 3.2.1.17
UniProt: P00720
Ligands: SO4
Pockets: 4 · best druggability 0.47

Structure

x-ray diffraction · 2 distinct chains · 60% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Lysozyme (EC 3.2.1.17)	protein	157	61% helix, 6% strand	P00720
D	Lysozyme (EC 3.2.1.17)	protein	160	58% helix, 6% strand	P00720

Ligands and binding sites

SO4 · Sulfate ion · ion · 8 copies · chains A, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	238	0.47	0.73	31	empty
2	191	0.45	0.74	24	empty
3	193	0.44	0.74	30	empty
4	159	0.41	0.73	24	empty

Compared structures

2B7X · Sequential reorganization of beta-sheet topology by insertion of a single strand · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00720
Elsewhere: RCSB PDB 2B7X · PDBe 2B7X · UniProt P00720

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