Research workbench

C.BCLI, control element of the bcli restriction-modification system

Analyse C.BCLI, control element of the bcli restriction-modification system in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2B5A
Type: protein
Length: 304 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C.BCLI
Pockets: 4 · best druggability 0.62

Structure

x-ray diffraction · 3 distinct chains · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	C.BCLI	protein	77	70% helix, 1% strand	—
B	C.BCLI	protein	75	72% helix, 1% strand	—
C, D	C.BCLI	protein	76	70% helix, 1% strand	—

Ligands and binding sites

ACY · Acetic acid · additive · 2 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	440	0.62	0.76	47	empty
2	95	0.44	0.79	15	empty
3	95	0.43	0.78	15	empty
4	84	0.41	0.78	14	empty

Interfaces

3 interfaces between chains.

A–B · 970 Å² buried · 12 hydrogen bonds · protein-protein
C–D · 939 Å² buried · 12 hydrogen bonds · protein-protein
B–C · 303 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

2B5A · C.BclI, Control Element of the BclI Restriction-Modification System · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2B5A · PDBe 2B5A

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