Research workbench
Guanine riboswitch C74U mutant bound to 2,6-diaminopurine
Analyse Guanine riboswitch C74U mutant bound to 2,6-diaminopurine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2B57
- Type
- RNA
- Length
- 65 nucleotides
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 65-mer
- Ligands
- NCO, 6AP
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 65-mer | rna | 65 | — | — |
Ligands and binding sites
- NCO · Cobalt hexammine(iii) · ligand · 9 copies · chains A
- 6AP · 9H-purine-2,6-diamine · ligand · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 825 | 0.71 | 0.78 | 36 | ACT, NCO |
| 2 | 190 | 0.44 | 0.75 | 18 | 6AP |
Compared structures
- 2B57 · Guanine Riboswitch C74U mutant bound to 2,6-diaminopurine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2B57 · PDBe 2B57
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