Research workbench
Structure of the D223N mutant of selenomonas ruminantium ptp-like phytase
Analyse Structure of the D223N mutant of selenomonas ruminantium ptp-like phytase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2B4P
- Type
- protein
- Length
- 627 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Myo-inositol hexaphosphate phosphohydrolase
- EC
- 3.1.3.72
- UniProt
- Q7WUJ1
- Ligands
- CL
- Pockets
- 5 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myo-inositol hexaphosphate phosphohydrolase (EC 3.1.3.72) | protein | 314 | 39% helix, 18% strand | Q7WUJ1 |
| B | Myo-inositol hexaphosphate phosphohydrolase (EC 3.1.3.72) | protein | 313 | 40% helix, 18% strand | Q7WUJ1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 363 | 0.61 | 0.77 | 30 | empty |
| 2 | 320 | 0.58 | 0.77 | 48 | MLI |
| 3 | 276 | 0.57 | 0.77 | 44 | MLI |
| 4 | 141 | 0.52 | 0.80 | 32 | empty |
| 5 | 111 | 0.49 | 0.81 | 25 | CL |
Interfaces
1 interface between chains.
- A–B · 711 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 2B4P · Structure of the D223N mutant of Selenomonas ruminantium PTP-like phytase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7WUJ1
- Elsewhere: RCSB PDB 2B4P · PDBe 2B4P · UniProt Q7WUJ1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.