Research workbench
Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting domain of NUP116P
Analyse Multiple conformations in the ligand-binding site of the yeast nuclear pore… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2AIV
- Type
- protein
- Length
- 149 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fragment of nucleoporin NUP116/NSP116
- UniProt
- Q02630
- Pockets
- 2 · best druggability 0.77
Structure
solution nmr · 1 distinct chain · 16% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fragment of nucleoporin NUP116/NSP116 | protein | 149 | 16% helix, 19% strand | Q02630 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 424 | 0.77 | 0.86 | 54 | empty |
| 2 | 150 | 0.49 | 0.78 | 23 | empty |
Compared structures
- 2AIV · Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting… · the same entry in another collection · chain A against A, TM-score 1.00
- Q02630 · AlphaFold monomer V2.0 prediction for nucleoporin NUP116/NSP116 (Q02630) · a predicted model of the same protein · chain A against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02630
- Elsewhere: RCSB PDB 2AIV · PDBe 2AIV · UniProt Q02630
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