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MolNFT v1 · #271642 · protein

AlphaFold monomer V2.0 prediction for nucleoporin NUP116/NSP116 (Q02630)

Q02630: “AlphaFold monomer V2.0 prediction for nucleoporin NUP116/NSP116 (Q02630)”. 4 pockets (best druggability 0.61). MolNFT v1 #271642 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q02630
Type
protein
Length
1,113 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9073C46348542FfE4327c3F363F9B51B22058e75
Molecule
Nucleoporin NUP116/NSP116
UniProt
Q02630
Pockets
4 · best druggability 0.61

Structure

1 distinct chain · 7% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANucleoporin NUP116/NSP116protein11137% helix, 5% strandQ02630

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15560.610.7566empty
21200.450.7824empty
31640.410.7326empty
4700.360.7720empty

Compared structures

  • 3PBP · Structure of the yeast heterotrimeric NUP82-NUP159-NUP116 nucleoporin complex · an experimental structure of the same protein · chain A against B, TM-score 0.13
  • 3PBP · Structure of the yeast heterotrimeric Nup82-Nup159-Nup116 nucleoporin complex · an experimental structure of the same protein · chain A against B, TM-score 0.13
  • 2AIV · Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting… · an experimental structure of the same protein · chain A against A, TM-score 0.12
  • 2AIV · Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting… · an experimental structure of the same protein · chain A against A, TM-score 0.12

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