NMR solution structure of the C-myc-max heterodimeric leucine zipper, 40 structures

Structure

solution nmr · 2 distinct chains · 83% helix, 0% strand (DSSP).

Ligands and binding sites

• ACE · Acetyl group · ligand · 2 copies · chains A, B
• NH2 · Amino group · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 802 Ų buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 covalent, 1 disulfide (covalent ligand, disulfide).

Compared structures

• 2A93 · NMR solution structure of the C-myc-max heterodimeric leucine zipper, 40 structures · the same entry in another collection · chain A against A, TM-score 1.00
• P01106 · AlphaFold monomer V2.0 prediction for myc proto-oncogene protein (P01106) · a predicted model of the same protein · chain A against A, TM-score 0.81
• P28574 · AlphaFold monomer V2.0 prediction for protein max (P28574) · a predicted model of the same protein · chain B against A, TM-score 0.74

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P01106
• Every structure of UniProt P28574
• Elsewhere: RCSB PDB 2A93 · PDBe 2A93 · UniProt P01106 · UniProt P28574