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Crystal structure of a putative transcriptional regulator (NE_1354) from nitrosomonas europaea at 1.90 a resolution

Analyse Crystal structure of a putative transcriptional regulator (NE_1354) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2A6C
Type: protein
Length: 152 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Helix-turn-helix motif
UniProt: Q82UW4
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 59% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Helix-turn-helix motif	protein	76	59% helix, 0% strand	Q82UW4

Ligands and binding sites

GOL · Glycerol · additive · 2 copies · chains B
EDO · 1,2-ethanediol · additive · chains A
CIT · Citric acid · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	130	0.43	0.75	22	GOL

Interfaces

1 interface between chains.

A–B · 242 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

2A6C · Crystal structure of a putative transcriptional regulator (NE_1354) from nitrosomonas… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q82UW4
Elsewhere: RCSB PDB 2A6C · PDBe 2A6C · UniProt Q82UW4

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