Research workbench
Crystal structure of SIAH1 sbd bound to the peptide ekpaavvapittg from sip
Analyse Crystal structure of SIAH1 sbd bound to the peptide ekpaavvapittg from sip in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2A25
- Type
- protein
- Length
- 155 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin ligase SIAH1; Calcyclin-binding protein peptide
- EC
- 6.3.2.-
- UniProt
- Q8IUQ4, Q9HB71
- Ligands
- ZN
Structure
x-ray diffraction · 2 distinct chains · 15% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin ligase SIAH1 (EC 6.3.2.-) | protein | 146 | 16% helix, 49% strand | Q8IUQ4 |
| B | Calcyclin-binding protein peptide | protein | 9 | 0% helix, 44% strand | Q9HB71 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 577 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 2A25 · Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP · the same entry in another collection · chain A against A, TM-score 1.00
- Q8IUQ4 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SIAH1 (Q8IUQ4) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q9HB71 · AlphaFold monomer V2.0 prediction for calcyclin-binding protein (Q9HB71) · a predicted model of the same protein · chain B against A, TM-score 0.44
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IUQ4
- Every structure of UniProt Q9HB71
- Elsewhere: RCSB PDB 2A25 · PDBe 2A25 · UniProt Q8IUQ4 · UniProt Q9HB71
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.