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Co-crystal structure of ORF2 an aromatic prenyl transferase from streptomyces sp. strain CL190 complexed with gpp

Analyse Co-crystal structure of ORF2 an aromatic prenyl transferase from streptomyces… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZCW
Type: protein
Length: 302 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aromatic prenyltransferase
UniProt: Q4R2T2
Ligands: GPP, MG, NO3
Pockets: 1 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aromatic prenyltransferase	protein	302	39% helix, 25% strand	Q4R2T2

Ligands and binding sites

GPP · Geranyl diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A
NO3 · Nitrate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	532	0.81	0.87	71	MG, GPP

Compared structures

1ZCW · Co-crystal structure of Orf2 an aromatic prenyl transferase from Streptomyces sp. strain… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4R2T2
Elsewhere: RCSB PDB 1ZCW · PDBe 1ZCW · UniProt Q4R2T2

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