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Inferential structure determination of the fyn SH3 domain using noesy data from a 15N,H2 enriched protein

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PDB: 1ZBJ
Type: protein
Length: 59 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proto-oncogene tyrosine-protein kinase fyn
EC: 2.7.1.112
UniProt: P06241
Pockets: 1 · best druggability 0.54

Structure

solution nmr · 1 distinct chain · 0% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proto-oncogene tyrosine-protein kinase fyn (EC 2.7.1.112)	protein	59	0% helix, 15% strand	P06241

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.54	0.83	16	empty

Compared structures

1ZBJ · Inferential Structure Determination of the Fyn SH3 domain using NOESY data from a 15N,H2… · the same entry in another collection · chain A against A, TM-score 1.00
P06241 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase fyn (P06241) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06241
Elsewhere: RCSB PDB 1ZBJ · PDBe 1ZBJ · UniProt P06241

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