Research workbench

Co-crystal structure of ORF2 an aromatic prenyl transferase from streptomyces sp. strain CL190 complexed with gspp and 1,6-dihydroxynaphtalene

Analyse Co-crystal structure of ORF2 an aromatic prenyl transferase from streptomyces… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZB6
Type: protein
Length: 301 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aromatic prenyltransferase
Ligands: GST, DIN, MG, NO3
Pockets: 1 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aromatic prenyltransferase	protein	301	37% helix, 24% strand	—

Ligands and binding sites

GST · Geranyl S-thiolodiphosphate · ligand · chains A
DIN · 1,6-dihydroxy naphthalene · ligand · chains A
MG · Magnesium ion · metal · chains A
NO3 · Nitrate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	660	0.82	0.86	71	MG, GST, DIN

Compared structures

1ZB6 · Co-Crystal Structure of ORF2 an Aromatic Prenyl Transferase from Streptomyces sp. strain… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1ZB6 · PDBe 1ZB6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.