Research workbench
Structural insight into the binding diversity between the tyr- phosphorylated human ephrinbs and NCK2 SH2 domain
Analyse Structural insight into the binding diversity between the tyr- phosphorylated… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1Z3K
- Type
- protein
- Length
- 98 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytoplasmic protein NCK2
- UniProt
- O43639
- Pockets
- 2 · best druggability 0.37
Structure
solution nmr · 1 distinct chain · 10% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytoplasmic protein NCK2 | protein | 98 | 10% helix, 33% strand | O43639 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.37 | 0.78 | 18 | empty |
| 2 | 53 | 0.28 | 0.75 | 16 | empty |
Compared structures
- 1Z3K · Structural Insight into the Binding Diversity between the Tyr-Phosphorylated Human… · the same entry in another collection · chain A against A, TM-score 1.00
- O43639 · AlphaFold monomer V2.0 prediction for cytoplasmic protein NCK2 (O43639) · a predicted model of the same protein · chain A against A, TM-score 0.65
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43639
- Elsewhere: RCSB PDB 1Z3K · PDBe 1Z3K · UniProt O43639
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