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GDP-bound RAB14 GTPase

Analyse GDP-bound RAB14 GTPase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1Z0F
Type: protein
Length: 167 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RAB14, member RAS oncogene family
UniProt: P61106
Ligands: GDP, MG
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAB14, member RAS oncogene family	protein	167	37% helix, 26% strand	P61106

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.42	0.75	27	MG, GDP

Compared structures

1Z0F · GDP-Bound Rab14 GTPase · the same entry in another collection · chain A against A, TM-score 1.00
P61106 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-14 (P61106) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61106
Elsewhere: RCSB PDB 1Z0F · PDBe 1Z0F · UniProt P61106

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