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Crystal structure of stringent starvation protein a (sspa), an RNA polymerase-associated transcription factor

Analyse Crystal structure of stringent starvation protein a (sspa), an RNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1YY7
Type
protein
Length
410 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Stringent starvation protein a
UniProt
Q8ZB63
Pockets
5 · best druggability 0.60

Structure

x-ray diffraction · 2 distinct chains · 57% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AStringent starvation protein aprotein20659% helix, 10% strandQ8ZB63
BStringent starvation protein aprotein20455% helix, 10% strandQ8ZB63

Ligands and binding sites

  • CIT · Citric acid · additive · 2 copies · chains B, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13970.600.7646CIT
2990.360.7425empty
3810.330.7415empty
4880.310.7217empty
5650.260.7217empty

Interfaces

1 interface between chains.

  • A–B · 1194 Ų buried · 23 hydrogen bonds · protein-protein

Compared structures

  • 1YY7 · Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated… · the same entry in another collection · chain A against A, TM-score 1.00

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