Research workbench
Crystal structure of bovine HSC70(AA1-554)E213A/D214A mutant
Analyse Crystal structure of bovine HSC70(AA1-554)E213A/D214A mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YUW
- Type
- protein
- Length
- 554 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock cognate 71 kda protein
- UniProt
- P19120
- Pockets
- 6 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock cognate 71 kda protein | protein | 554 | 30% helix, 30% strand | P19120 |
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 143 | 0.72 | 0.92 | 32 | empty |
| 2 | 431 | 0.63 | 0.77 | 45 | empty |
| 3 | 428 | 0.61 | 0.76 | 31 | empty |
| 4 | 302 | 0.60 | 0.78 | 39 | empty |
| 5 | 280 | 0.57 | 0.77 | 34 | empty |
Compared structures
- 1YUW · crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant · the same entry in another collection · chain A against A, TM-score 1.00
- P19120 · AlphaFold monomer V2.0 prediction for heat shock cognate 71 kda protein (P19120) · a predicted model of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19120
- Elsewhere: RCSB PDB 1YUW · PDBe 1YUW · UniProt P19120
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