Research workbench

Yersinia ptpase complexed with tungstate

Analyse Yersinia ptpase complexed with tungstate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1YTW
Type: protein
Length: 283 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Yersinia protein tyrosine phosphatase
EC: 3.1.3.48
UniProt: P15273
Ligands: WO4, SO4
Pockets: 2 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Yersinia protein tyrosine phosphatase (EC 3.1.3.48)	protein	283	38% helix, 20% strand	P15273

Ligands and binding sites

WO4 · Tungstate(vi)ion · ion · chains A
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	108	0.42	0.77	23	empty
2	51	0.39	0.81	13	empty

Compared structures

1YTW · Yersinia ptpase complexed with tungstate · the same entry in another collection · chain A against A, TM-score 1.00
P15273 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase yoph (P15273) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15273
Elsewhere: RCSB PDB 1YTW · PDBe 1YTW · UniProt P15273

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.