Research workbench
Hypothetical protein PA3270 from pseudomonas aeruginosa in complex with CoA
Analyse Hypothetical protein PA3270 from pseudomonas aeruginosa in complex with CoA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YRE
- Type
- protein
- Length
- 739 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein PA3270
- Ligands
- COA
- Pockets
- 3 · best druggability 0.87
Structure
x-ray diffraction · 3 distinct chains · 35% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical protein PA3270 | protein | 183 | 34% helix, 36% strand | — |
| B, D | Hypothetical protein PA3270 | protein | 187 | 35% helix, 35% strand | — |
| C | Hypothetical protein PA3270 | protein | 182 | 35% helix, 36% strand | — |
Ligands and binding sites
- COA · Coenzyme A · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1032 | 0.87 | 0.88 | 113 | COA |
| 2 | 980 | 0.86 | 0.87 | 107 | COA |
| 3 | 616 | 0.70 | 0.78 | 46 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1039 Ų buried · 30 hydrogen bonds · protein-protein
- C–D · 999 Ų buried · 25 hydrogen bonds · protein-protein
- A–D · 273 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 254 Ų buried · 4 hydrogen bonds · protein-protein
- B–D · 12 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1YRE · Hypothetical protein PA3270 from Pseudomonas aeruginosa in complex with CoA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1YRE · PDBe 1YRE
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.