Research workbench
Human oxidized low density lipoprotein receptor lox-1 C2 space group
Analyse Human oxidized low density lipoprotein receptor lox-1 C2 space group in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YPU
- Type
- protein
- Length
- 266 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oxidised low density lipoprotein (lectin-like) receptor 1
- UniProt
- P78380
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · 2 distinct chains · 16% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxidised low density lipoprotein (lectin-like) receptor 1 | protein | 131 | 15% helix, 33% strand | P78380 |
| B | Oxidised low density lipoprotein (lectin-like) receptor 1 | protein | 135 | 17% helix, 32% strand | P78380 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.58 | 0.84 | 28 | empty |
| 2 | 50 | 0.34 | 0.79 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 967 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 1YPU · Human Oxidized Low Density Lipoprotein Receptor LOX-1 C2 Space Group · the same entry in another collection · chain B against B, TM-score 1.00
- P78380 · AlphaFold monomer V2.0 prediction for oxidized low-density lipoprotein receptor 1 (P78380) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P78380
- Elsewhere: RCSB PDB 1YPU · PDBe 1YPU · UniProt P78380
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