UniProt P78380
Oxidized low-density lipoprotein receptor 1 (P78380)
Oxidized low-density lipoprotein receptor 1 (UniProt P78380): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P78380
- Protein
- Oxidized low-density lipoprotein receptor 1
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
Structures
18 records of P78380 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YPO | Human Oxidized Low Density Lipoprotein Receptor LOX-1 P3 1 21 Space Group | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1YPO | Human oxidized low density lipoprotein receptor lox-1 P3 1 21 space group | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1YPQ | Human Oxidized Low Density Lipoprotein Receptor LOX-1 Dioxane Complex | x-ray diffraction | A, B | — | — |
| 1YPQ | Human oxidized low density lipoprotein receptor lox-1 dioxane complex | x-ray diffraction | A, B | — | — |
| 1YPU | Human Oxidized Low Density Lipoprotein Receptor LOX-1 C2 Space Group | x-ray diffraction | A, B | — | — |
| 1YPU | Human oxidized low density lipoprotein receptor lox-1 C2 space group | x-ray diffraction | A, B | — | — |
| 1YXJ | Crystal structure of human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) at low pH | x-ray diffraction | A, B | — | — |
| 1YXJ | Crystal structure of human lectin-like oxidized low-density lipoprotein receptor 1 (lox-1) at low pH | x-ray diffraction | A, B | — | — |
| 1YXK | Crystal structure of human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1)… | x-ray diffraction | A, B | — | — |
| 1YXK | Crystal structure of human lectin-like oxidized low-density lipoprotein receptor 1 (lox-1)… | x-ray diffraction | A, B | — | — |
| 3VLG | Crystal structure of the W150A mutant LOX-1 CTLD showing impaired OxLDL binding | x-ray diffraction | A | — | — |
| 3VLG | Crystal structure of the W150A mutant lox-1 ctld showing impaired oxldl binding | x-ray diffraction | A | — | — |
| 6TL7 | Crystal structure of lectin-like ox-LDL receptor 1 (P212121) | x-ray diffraction | A, B | NI | — |
| 6TL9 | Crystal structure of lectin-like ox-LDL receptor 1 in complex with bi-0115 | x-ray diffraction | A, B, C, D, E, F, G, H | NJT | — |
| 6TL9 | Crystal structure of lectin-like ox-LDL receptor 1 in complex with bi- 0115 | x-ray diffraction | A, B, C, D, E, F, G, H | NJT | — |
| 6TLA | Crystal structure of lectin-like ox-LDL receptor 1 (C 1 2 1) | x-ray diffraction | A, B, C | — | — |
| 7R8U | LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis | x-ray diffraction | AAA, BBB | — | — |
| P78380 | AlphaFold monomer V2.0 prediction for oxidized low-density lipoprotein receptor 1 (P78380) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6TLA chain C against the predicted model P78380: TM-score 0.99, RMSD 0.50 Å
- 1YXJ chain A against the predicted model P78380: TM-score 0.98, RMSD 0.53 Å
- 1YXJ chain A against the predicted model P78380: TM-score 0.98, RMSD 0.53 Å
- 6TL9 chain A against the predicted model P78380: TM-score 0.98, RMSD 0.65 Å
- 6TL9 chain A against the predicted model P78380: TM-score 0.98, RMSD 0.65 Å
- 1YXJ chain B against the predicted model P78380: TM-score 0.98, RMSD 0.58 Å
- 1YXJ chain B against the predicted model P78380: TM-score 0.98, RMSD 0.58 Å
- 1YXK chain A against the predicted model P78380: TM-score 0.98, RMSD 0.71 Å
- 1YXK chain A against the predicted model P78380: TM-score 0.98, RMSD 0.71 Å
- 3VLG chain A against the predicted model P78380: TM-score 0.98, RMSD 0.62 Å
Elsewhere
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