Research workbench

Lipoxygenase-1 (soybean) at 100K

Analyse Lipoxygenase-1 (soybean) at 100K in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1YGE
Type: protein
Length: 839 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipoxygenase-1
EC: 1.13.11.12
UniProt: P08170
Ligands: FE
Pockets: 16 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipoxygenase-1 (EC 1.13.11.12)	protein	839	42% helix, 14% strand	P08170

Ligands and binding sites

FE · Fe (III) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	680	0.84	0.88	52	empty
2	65	0.74	0.98	22	empty
3	396	0.69	0.81	45	empty
4	314	0.59	0.78	40	empty
5	169	0.47	0.76	21	empty

Compared structures

1YGE · Lipoxygenase-1 (soybean) at 100K · the same entry in another collection · chain A against A, TM-score 1.00
P08170 · AlphaFold monomer V2.0 prediction for seed linoleate 13S-lipoxygenase-1 (P08170) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08170
Elsewhere: RCSB PDB 1YGE · PDBe 1YGE · UniProt P08170

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