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Structure of N-terminal domain IRSP53/BAIAP2

Analyse Structure of N-terminal domain IRSP53/BAIAP2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1Y2O
Type: protein
Length: 496 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BAI1-associated protein 2 isoform 1
UniProt: Q9UQB8
Pockets: 1 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 90% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	BAI1-associated protein 2 isoform 1	protein	248	90% helix, 0% strand	Q9UQB8

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	249	0.85	0.96	42	empty

Interfaces

1 interface between chains.

A–B · 3976 Å² buried · 31 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 16 modified (engineered).

Compared structures

1Y2O · Structure of N-terminal domain IRSp53/BAIAP2 · the same entry in another collection · chain A against A, TM-score 1.00
Q9UQB8 · AlphaFold monomer V2.0 prediction for brain-specific angiogenesis inhibitor 1-associated… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UQB8
Elsewhere: RCSB PDB 1Y2O · PDBe 1Y2O · UniProt Q9UQB8

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