Zinc fingers as protein recognition motifs: structural basis for the gata-1/FRIEND of gata interaction

Structure

solution nmr · 2 distinct chains · 19% helix, 8% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 530 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

• 1Y0J · Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of… · the same entry in another collection · chain A against A, TM-score 1.00
• P17679 · AlphaFold monomer V2.0 prediction for erythroid transcription factor (P17679) · a predicted model of the same protein · chain A against A, TM-score 0.70
• Q9VPQ6 · AlphaFold monomer V2.0 prediction for zinc finger protein ush (Q9VPQ6) · a predicted model of the same protein · chain B against A, TM-score 0.54

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P17679
• Every structure of UniProt Q9VPQ6
• Elsewhere: RCSB PDB 1Y0J · PDBe 1Y0J · UniProt P17679 · UniProt Q9VPQ6