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Structure of aminopeptidase

Analyse Structure of aminopeptidase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1XJO
Type: protein
Length: 271 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aminopeptidase
EC: 3.4.11.-
UniProt: P80561
Ligands: ZN, CA, PO4
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aminopeptidase (EC 3.4.11.-)	protein	271	42% helix, 21% strand	P80561

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A
CA · Calcium ion · metal · chains A
PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.31	0.74	18	PO4

Modifications

Observed in the structure: 1 disulfide, 1 modified (disulfide, oxidation).

Compared structures

1XJO · Structure of aminopeptidase · the same entry in another collection · chain A against A, TM-score 1.00
P80561 · AlphaFold monomer V2.0 prediction for aminopeptidase S (P80561) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P80561
Elsewhere: RCSB PDB 1XJO · PDBe 1XJO · UniProt P80561

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