Research workbench
Clathrin D6 coat
Analyse Clathrin D6 coat in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1XI4
- Type
- protein
- Length
- 15,300 residues
- Chains
- 18
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Clathrin heavy chain; Clathrin light chain a
- UniProt
- P49951, P04973
- Pockets
- 20 · best druggability 0.67
Structure
electron microscopy · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I | Clathrin heavy chain | protein | 1630 | 0% helix, 0% strand | P49951 |
| J, K, L, M, N, O, P, Q, R | Clathrin light chain a | protein | 70 | 0% helix, 0% strand | P04973 |
Pockets
20 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 600 | 0.67 | 0.75 | 94 | empty |
| 2 | 514 | 0.65 | 0.75 | 78 | empty |
| 3 | 424 | 0.62 | 0.74 | 69 | empty |
| 4 | 344 | 0.57 | 0.73 | 54 | empty |
| 5 | 256 | 0.53 | 0.74 | 50 | empty |
Interfaces
25 interfaces between chains.
- F–G · 567 Ų buried · 0 hydrogen bonds · protein-protein
- C–D · 391 Ų buried · 0 hydrogen bonds · protein-protein
- A–F · 320 Ų buried · 0 hydrogen bonds · protein-protein
- E–H · 244 Ų buried · 0 hydrogen bonds · protein-protein
- G–I · 129 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1XI4 · Clathrin D6 Coat · the same entry in another collection · chain N against N, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49951
- Every structure of UniProt P04973
- Elsewhere: RCSB PDB 1XI4 · PDBe 1XI4 · UniProt P49951 · UniProt P04973
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