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Plasminogen activator inhibitor-1

Analyse Plasminogen activator inhibitor-1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1C5G
Type: protein
Length: 379 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plasminogen activator inhibitor-1
UniProt: P05121
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plasminogen activator inhibitor-1	protein	379	28% helix, 34% strand	P05121

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	158	0.52	0.79	24	empty

Compared structures

1C5G · Plasminogen activator inhibitor-1 · the same entry in another collection · chain A against A, TM-score 1.00
P05121 · AlphaFold monomer V2.0 prediction for plasminogen activator inhibitor 1 (P05121) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05121
Elsewhere: RCSB PDB 1C5G · PDBe 1C5G · UniProt P05121

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