Crystal structure of aa-X-bp-I, a snake venom protein with the activity of binding to coagulation factor X from agkistrodon acutus

Structure

x-ray diffraction · 2 distinct chains · 22% helix, 32% strand (DSSP).

Ligands and binding sites

• CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1961 Ų buried · 30 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

• 1WT9 · crystal structure of Aa-X-bp-I, a snake venom protein with the activity of binding to… · the same entry in another collection · chain A against A, TM-score 1.00
• Q9DEF9 · AlphaFold monomer V2.0 prediction for snaclec anticoagulant protein subunit a (Q9DEF9) · a predicted model of the same protein · chain A against A, TM-score 0.92
• Q9DEF8 · AlphaFold monomer V2.0 prediction for snaclec anticoagulant protein subunit B (Q9DEF8) · a predicted model of the same protein · chain B against A, TM-score 0.92

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9DEF9
• Every structure of UniProt Q9DEF8
• Elsewhere: RCSB PDB 1WT9 · PDBe 1WT9 · UniProt Q9DEF9 · UniProt Q9DEF8