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Crystal structure of a PB1 domain complex of protein kinase C iota and PAR6 alpha

Analyse Crystal structure of a PB1 domain complex of protein kinase C iota and PAR6… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1WMH
Type
protein
Length
165 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein kinase C, iota type; Partitioning defective-6 homolog alpha
EC
2.7.1.37
UniProt
P41743, Q9NPB6

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 35% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein kinase C, iota type (EC 2.7.1.37)protein8329% helix, 34% strandP41743
BPartitioning defective-6 homolog alphaprotein8226% helix, 37% strandQ9NPB6

Interfaces

1 interface between chains.

  • A–B · 636 Ų buried · 12 hydrogen bonds · protein-protein

Compared structures

  • 1WMH · Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9NPB6 · AlphaFold monomer V2.0 prediction for partitioning defective 6 homolog alpha (Q9NPB6) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • P41743 · AlphaFold monomer V2.0 prediction for protein kinase C iota type (P41743) · a predicted model of the same protein · chain A against A, TM-score 0.95

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