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Crystal structure of alkaline serine protease kp-43 from bacillus sp. ksm-KP43 (1.30 ångström, 100 K)

Analyse Crystal structure of alkaline serine protease kp-43 from bacillus sp. ksm-KP43… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WMD
Type: protein
Length: 434 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protease
EC: 3.4.21.-
UniProt: Q93UV9
Ligands: CA, SO4
Pockets: 2 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protease (EC 3.4.21.-)	protein	434	21% helix, 26% strand	Q93UV9

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A
SO4 · Sulfate ion · ion · chains A
DIO · 1,4-diethylene dioxide · additive · 2 copies · chains A
GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.37	0.74	28	DIO
2	55	0.26	0.73	18	empty

Compared structures

1WMD · Crystal Structure of alkaline serine protease KP-43 from Bacillus sp. KSM-KP43 (1.30… · the same entry in another collection · chain A against A, TM-score 1.00

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Every structure of UniProt Q93UV9
Elsewhere: RCSB PDB 1WMD · PDBe 1WMD · UniProt Q93UV9

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