Research workbench
Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
Analyse Structure of a thrombospondin C-terminal fragment reveals a novel calcium core… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1UX6
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thrombospondin-1
- UniProt
- P07996
- Ligands
- CA
- Pockets
- 3 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thrombospondin-1 | protein | 335 | 7% helix, 32% strand | P07996 |
Ligands and binding sites
- CA · Calcium ion · metal · 16 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 299 | 0.58 | 0.77 | 29 | empty |
| 2 | 127 | 0.48 | 0.79 | 22 | empty |
| 3 | 50 | 0.42 | 0.84 | 15 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 1UX6 · Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the… · the same entry in another collection · chain A against A, TM-score 1.00
- P07996 · AlphaFold monomer V2.0 prediction for thrombospondin-1 (P07996) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07996
- Elsewhere: RCSB PDB 1UX6 · PDBe 1UX6 · UniProt P07996
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.