Research workbench
Crystal structure of autoinhibited form of tandem SH3 domain of P47PHOX
Analyse Crystal structure of autoinhibited form of tandem SH3 domain of P47PHOX in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1UEC
- Type
- protein
- Length
- 177 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neutrophil cytosol factor 1
- UniProt
- P14598
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neutrophil cytosol factor 1 | protein | 177 | 15% helix, 25% strand | P14598 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 173 | 0.52 | 0.79 | 30 | empty |
| 2 | 127 | 0.45 | 0.76 | 15 | empty |
| 3 | 51 | 0.23 | 0.72 | 14 | empty |
Compared structures
- 1UEC · Crystal structure of autoinhibited form of tandem SH3 domain of p47phox · the same entry in another collection · chain A against A, TM-score 1.00
- P14598 · AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 1 (P14598) · a predicted model of the same protein · chain A against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14598
- Elsewhere: RCSB PDB 1UEC · PDBe 1UEC · UniProt P14598
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