Research workbench
NMR studies of human general transcription factor tfiib: dynamics and interaction with VP16 activation domain, 20 structures
Analyse NMR studies of human general transcription factor tfiib: dynamics and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1TFB
- Type
- protein
- Length
- 206 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tfiib
- UniProt
- Q00403
- Pockets
- 3 · best druggability 0.38
Structure
solution nmr · 1 distinct chain · 51% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tfiib | protein | 206 | 51% helix, 0% strand | Q00403 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.38 | 0.76 | 16 | empty |
| 2 | 56 | 0.32 | 0.76 | 10 | empty |
| 3 | 61 | 0.32 | 0.76 | 16 | empty |
Compared structures
- 1TFB · NMR studies of human general transcription factor tfiib: dynamics and interaction with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q00403 · AlphaFold monomer V2.0 prediction for transcription initiation factor iib (Q00403) · a predicted model of the same protein · chain A against A, TM-score 0.54
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00403
- Elsewhere: RCSB PDB 1TFB · PDBe 1TFB · UniProt Q00403
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