Research workbench
Crystal structure of a phosphatase resistant mutant of sporulation response regulator SPO0F from bacillus subtilis
Analyse Crystal structure of a phosphatase resistant mutant of sporulation response… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SRR
- Type
- protein
- Length
- 360 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sporulation response regulatory protein
- UniProt
- P06628
- Ligands
- CA
- Pockets
- 2 · best druggability 0.52
Structure
x-ray diffraction · 3 distinct chains · 46% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sporulation response regulatory protein | protein | 119 | 46% helix, 20% strand | P06628 |
| B | Sporulation response regulatory protein | protein | 120 | 48% helix, 26% strand | P06628 |
| C | Sporulation response regulatory protein | protein | 121 | 45% helix, 20% strand | P06628 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.52 | 0.78 | 26 | empty |
| 2 | 138 | 0.43 | 0.75 | 23 | empty |
Interfaces
1 interface between chains.
- B–C · 425 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 1SRR · Crystal structure of a phosphatase resistant mutant of sporulation response regulator… · the same entry in another collection · chain A against A, TM-score 1.00
- P06628 · AlphaFold monomer V2.0 prediction for sporulation initiation phosphotransferase F (P06628) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06628
- Elsewhere: RCSB PDB 1SRR · PDBe 1SRR · UniProt P06628
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