Research workbench
X-ray crystal structure protein SP1951 of streptococcus pneumoniae. northeast structural genomics consortium target SPR27.
Analyse X-ray crystal structure protein SP1951 of streptococcus pneumoniae. northeast… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1SQS
- Type
- protein
- Length
- 464 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein
- UniProt
- Q97NR6
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Conserved hypothetical protein | protein | 232 | 47% helix, 16% strand | Q97NR6 |
Ligands and binding sites
- TLA · L(+)-tartaric acid · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1002 | 0.81 | 0.82 | 116 | TLA |
| 2 | 116 | 0.48 | 0.80 | 24 | empty |
| 3 | 56 | 0.38 | 0.80 | 18 | empty |
| 4 | 51 | 0.27 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1359 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 1SQS · X-Ray Crystal Structure Protein SP1951 of Streptococcus pneumoniae. Northeast Structural… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97NR6
- Elsewhere: RCSB PDB 1SQS · PDBe 1SQS · UniProt Q97NR6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.