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Plasmodium falciparum homolog of uridine PHOSPHORYLASE/PURINE nucleoside phosphorylase

Analyse Plasmodium falciparum homolog of uridine PHOSPHORYLASE/PURINE nucleoside… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SQ6
Type: protein
Length: 225 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uridine phosphorylase, putative
EC: 2.4.2.3
UniProt: Q8I3X4
Ligands: SO4
Pockets: 1 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uridine phosphorylase, putative (EC 2.4.2.3)	protein	225	33% helix, 31% strand	Q8I3X4

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	211	0.51	0.76	32	SO4

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

1SQ6 · Plasmodium falciparum homolog of Uridine phosphorylase/Purine nucleoside phosphorylase · the same entry in another collection · chain A against A, TM-score 1.00
Q8I3X4 · AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (Q8I3X4) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8I3X4
Elsewhere: RCSB PDB 1SQ6 · PDBe 1SQ6 · UniProt Q8I3X4

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