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Solution structure of the R1R2 domains of talin

Analyse Solution structure of the R1R2 domains of talin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SJ8
Type: protein
Length: 297 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Talin 1
UniProt: P26039
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 75% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Talin 1	protein	297	75% helix, 0% strand	P26039

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	145	0.50	0.79	22	empty
2	55	0.38	0.80	13	empty
3	80	0.33	0.74	21	empty

Compared structures

1SJ8 · Solution Structure of the R1R2 Domains of Talin · the same entry in another collection · chain A against A, TM-score 1.00
P26039 · AlphaFold monomer V2.0 prediction for talin-1 (P26039) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26039
Elsewhere: RCSB PDB 1SJ8 · PDBe 1SJ8 · UniProt P26039

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