Research workbench

Crystal structure of a C75U mutant hepatitis delta virus ribozyme precursor, in CU2+ solution

Analyse Crystal structure of a C75U mutant hepatitis delta virus ribozyme precursor, in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SJ4
Type: protein + RNA
Length: 168 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Precursor form of the hepatitis delta virus ribozyme; Small nuclear ribonucleoprotein a
UniProt: P09012
Pockets: 5 · best druggability 0.61

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
R	Precursor form of the hepatitis delta virus ribozyme	rna	73	—	—
P	Small nuclear ribonucleoprotein a	protein	95	32% helix, 24% strand	P09012

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	383	0.61	0.78	26	empty
2	396	0.53	0.74	25	empty
3	307	0.50	0.73	17	empty
4	100	0.38	0.77	13	empty
5	61	0.33	0.77	15	empty

Interfaces

1 interface between chains.

R–P · 952 Å² buried · 32 hydrogen bonds · protein-nucleic

Compared structures

1SJ4 · Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+… · the same entry in another collection · chain R against R, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09012
Elsewhere: RCSB PDB 1SJ4 · PDBe 1SJ4 · UniProt P09012

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.