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Crystal structure of pseudomonas aeruginosa udp-N-acetylglucosamine 4- epimerase complexed with udp-N-acetylgalactosamine

Analyse Crystal structure of pseudomonas aeruginosa udp-N-acetylglucosamine 4… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1SB8
Type: protein
Length: 341 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Wbpp
EC: 5.1.3.7
Ligands: NAD, UD2
Pockets: 3 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Wbpp (EC 5.1.3.7)	protein	341	46% helix, 16% strand	—

Ligands and binding sites

NAD · Nicotinamide-adenine-dinucleotide · ligand · chains A
UD2 · Uridine-diphosphate-N-acetylgalactosamine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	815	0.85	0.87	75	NAD, UD2
2	92	0.38	0.76	17	empty
3	51	0.30	0.76	17	empty

Compared structures

1SB8 · Crystal structure of Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase complexed… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1SB8 · PDBe 1SB8

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