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Crystal structure of kv channel-interacting protein 1 (kchip-1)

Analyse Crystal structure of kv channel-interacting protein 1 (kchip-1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1S1E
Type: protein
Length: 181 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Kv channel interacting protein 1
UniProt: Q9NZI2
Ligands: CA
Pockets: 2 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 65% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Kv channel interacting protein 1	protein	181	65% helix, 3% strand	Q9NZI2

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.55	0.80	18	empty
2	69	0.40	0.79	14	empty

Compared structures

1S1E · Crystal Structure of Kv Channel-interacting protein 1 (KChIP-1) · the same entry in another collection · chain A against A, TM-score 1.00
Q9NZI2 · AlphaFold monomer V2.0 prediction for kv channel-interacting protein 1 (Q9NZI2) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NZI2
Elsewhere: RCSB PDB 1S1E · PDBe 1S1E · UniProt Q9NZI2

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