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Basic fibroblast growth factor (FGF-2) mutant with cys 78 replaced by ser and cys 96 replaced by ser, NMR

Analyse Basic fibroblast growth factor (FGF-2) mutant with cys 78 replaced by ser and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1BLD
Type
protein
Length
155 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Basic fibroblast growth factor
UniProt
P09038
Pockets
2 · best druggability 0.60

Structure

solution nmr · 1 distinct chain · 2% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ABasic fibroblast growth factorprotein1552% helix, 34% strandP09038

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13040.600.7828empty
2550.360.7917empty

Compared structures

  • 1BLD · Basic fibroblast growth factor (FGF-2) mutant with cys 78 replaced by ser and cys 96… · the same entry in another collection · chain A against A, TM-score 1.00
  • P09038 · AlphaFold monomer V2.0 prediction for fibroblast growth factor 2 (P09038) · a predicted model of the same protein · chain A against A, TM-score 0.83

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