Research workbench

2.5 ångström resolution X-ray structure of aquaporin Z

Analyse 2.5 ångström resolution X-ray structure of aquaporin Z in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1RC2
Type: protein
Length: 462 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aquaporin Z
UniProt: P60844
Ligands: BGL
Pockets: 4 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B, A	Aquaporin Z	protein	231	70% helix, 0% strand	P60844

Ligands and binding sites

BGL · 2-O-octyl-beta-D-glucopyranose · ligand · 4 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.50	0.80	30	empty
2	142	0.45	0.76	33	empty
3	139	0.43	0.75	29	empty
4	125	0.42	0.76	29	empty

Compared structures

1RC2 · 2.5 Angstrom Resolution X-ray Structure of Aquaporin Z · the same entry in another collection · chain B against B, TM-score 1.00
P60844 · AlphaFold monomer V2.0 prediction for aquaporin Z (P60844) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P60844
Elsewhere: RCSB PDB 1RC2 · PDBe 1RC2 · UniProt P60844

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