Research workbench
Catalytic domain of plasminogen
Analyse Catalytic domain of plasminogen in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1QRZ
- Type
- protein
- Length
- 984 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plasminogen
- UniProt
- P00747
- Pockets
- 11 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 11% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Plasminogen | protein | 246 | 11% helix, 35% strand | P00747 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 712 | 0.71 | 0.78 | 80 | empty |
| 2 | 716 | 0.70 | 0.77 | 65 | empty |
| 3 | 265 | 0.58 | 0.78 | 40 | empty |
| 4 | 139 | 0.54 | 0.82 | 23 | empty |
| 5 | 126 | 0.50 | 0.80 | 25 | empty |
Interfaces
5 interfaces between chains.
- A–D · 482 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 452 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 366 Ų buried · 3 hydrogen bonds · protein-protein
- B–D · 49 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 37 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00747
- Elsewhere: RCSB PDB 1QRZ · PDBe 1QRZ · UniProt P00747
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.