Research workbench
Molecular architecture of the rotary motor in ATP synthase from yeast mitochondria
Analyse Molecular architecture of the rotary motor in ATP synthase from yeast… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1QO1
- Type
- protein
- Length
- 3,912 residues
- Chains
- 18
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATP synthase alpha chain; ATP synthase beta chain; ATP synthase gamma chain; ATP synthase…
- EC
- 3.6.1.34
- UniProt
- P19483, P00829, P05631, P00832, P00844
- Pockets
- 20 · best druggability 0.60
Structure
x-ray diffraction · 7 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ATP synthase alpha chain (EC 3.6.1.34) | protein | 487 | 0% helix, 0% strand | P19483 |
| C | ATP synthase alpha chain (EC 3.6.1.34) | protein | 492 | 0% helix, 0% strand | P19483 |
| D | ATP synthase beta chain (EC 3.6.1.34) | protein | 467 | 0% helix, 0% strand | P00829 |
| E, F | ATP synthase beta chain (EC 3.6.1.34) | protein | 466 | 0% helix, 0% strand | P00829 |
| G | ATP synthase gamma chain (EC 3.6.1.34) | protein | 122 | 0% helix, 0% strand | P05631 |
| J | ATP synthase delta chain (EC 3.6.1.34) | protein | 135 | 0% helix, 0% strand | P00832 |
| K, L, M, N, O, P, Q, R, S, T | ATP synthase protein 9 (EC 3.6.1.34) | protein | 79 | 0% helix, 0% strand | P00844 |
Pockets
20 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 407 | 0.60 | 0.74 | 90 | empty |
| 2 | 267 | 0.52 | 0.73 | 66 | empty |
| 3 | 233 | 0.52 | 0.74 | 45 | empty |
| 4 | 217 | 0.50 | 0.73 | 48 | empty |
| 5 | 205 | 0.47 | 0.73 | 48 | empty |
Interfaces
24 interfaces between chains.
- C–D · 463 Ų buried · 0 hydrogen bonds · protein-protein
- O–P · 431 Ų buried · 0 hydrogen bonds · protein-protein
- K–T · 410 Ų buried · 0 hydrogen bonds · protein-protein
- R–S · 410 Ų buried · 0 hydrogen bonds · protein-protein
- P–Q · 408 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1QO1 · Molecular Architecture of the Rotary Motor in ATP Synthase from Yeast Mitochondria · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19483
- Every structure of UniProt P00829
- Every structure of UniProt P05631
- Every structure of UniProt P00832
- Every structure of UniProt P00844
- Elsewhere: RCSB PDB 1QO1 · PDBe 1QO1 · UniProt P19483 · UniProt P00829 · UniProt P05631 · UniProt P00832 · UniProt P00844
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