UniProt P19483
ATP synthase subunit alpha, mitochondrial (P19483)
ATP synthase subunit alpha, mitochondrial (UniProt P19483): 91 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 77 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P19483
- Protein
- ATP synthase subunit alpha, mitochondrial
- Experimental structures
- 91
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 77 · 5 records with a druggable one
Structures
92 records of P19483 in the MolNFT archive: 91 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BMF | Bovine mitochondrial F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 1BMF | Bovine mitochondrial F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 1COW | Bovine mitochondrial F1-ATPase complexed with aurovertin B | x-ray diffraction | A, B, C | — | — |
| 1COW | Bovine mitochondrial F1-ATPase complexed with aurovertin B | x-ray diffraction | A, B, C | — | — |
| 1E1Q | Bovine mitochondrial F1-ATPase at 100K | x-ray diffraction | A, B, C | — | — |
| 1E1Q | Bovine mitochondrial F1-ATPase at 100K | x-ray diffraction | A, B, C | — | — |
| 1E1R | Bovine mitochondrial F1-ATPase inhibited by MG2+ADP and aluminium fluoride | x-ray diffraction | A, B, C | — | — |
| 1E1R | Bovine mitochondrial F1-ATPase inhibited by MG2+ADP and aluminium fluoride | x-ray diffraction | A, B, C | — | — |
| 1E79 | Bovine F1-ATPase inhibited by DCCD (dicyclohexylcarbodiimide) | x-ray diffraction | A, B, C | — | — |
| 1E79 | Bovine F1-ATPase inhibited by dccd (dicyclohexylcarbodiimide) | x-ray diffraction | A, B, C | — | — |
| 1EFR | Bovine mitochondrial F1-ATPase complexed with the peptide antibiotic efrapeptin | x-ray diffraction | A, B, C | — | — |
| 1EFR | Bovine mitochondrial F1-ATPase complexed with the peptide antibiotic efrapeptin | x-ray diffraction | A, B, C | — | — |
| 1H8E | (ADP.AlF4)2(ADP.SO4) bovine F1-ATPase (all three catalytic sites occupied) | x-ray diffraction | A, B, C | — | — |
| 1H8E | (ADP.ALF4)2(ADP.SO4) bovine F1-ATPase (all three catalytic sites occupied) | x-ray diffraction | A, B, C | — | — |
| 1H8H | Bovine mitochondrial F1-ATPase crystallised in the presence of 5mm AMPPNP | x-ray diffraction | A, B, C | — | — |
| 1H8H | Bovine mitochondrial F1-ATPase crystallised in the presence of 5MM amppnp | x-ray diffraction | A, B, C | — | — |
| 1NBM | The structure of bovine F1-ATPase covalently inhibited with 4-chloro-7-nitrobenzofurazan | x-ray diffraction | A, B, C | — | — |
| 1NBM | The structure of bovine F1-ATPase covalently inhibited with 4-chloro-7-nitrobenzofurazan | x-ray diffraction | A, B, C | — | — |
| 1OHH | BOVINE MITOCHONDRIAL F1-ATPASE complexed with the inhibitor protein IF1 | x-ray diffraction | A, B, C | — | — |
| 1OHH | Bovine mitochondrial F1-ATPase complexed with the inhibitor protein IF1 | x-ray diffraction | A, B, C | — | — |
| 1QO1 | Molecular Architecture of the Rotary Motor in ATP Synthase from Yeast Mitochondria | x-ray diffraction | A, B, C | — | — |
| 1QO1 | Molecular architecture of the rotary motor in ATP synthase from yeast mitochondria | x-ray diffraction | A, B, C | — | — |
| 1W0J | Beryllium fluoride inhibited bovine F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 1W0J | Beryllium fluoride inhibited bovine F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 1W0K | ADP inhibited bovine F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 1W0K | ADP inhibited bovine F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 2CK3 | Azide inhibited bovine F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 2CK3 | Azide inhibited bovine F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 2JDI | Ground state structure of F1-ATPase from bovine heart mitochondria (Bovine F1-ATPase crystallised… | x-ray diffraction | A, B, C | — | — |
| 2JDI | Ground state structure of F1-ATPase from bovine heart mitochondria (bovine F1-ATPase crystallised… | x-ray diffraction | A, B, C | — | — |
| 2JIZ | The Structure of F1-ATPase inhibited by resveratrol. | x-ray diffraction | A, B, C, H, I, J | — | — |
| 2JIZ | The structure of F1-ATPase inhibited by resveratrol. | x-ray diffraction | A, B, C, H, I, J | — | — |
| 2JJ1 | The Structure of F1-ATPase inhibited by piceatannol. | x-ray diffraction | A, B, C, H, I, J | — | — |
| 2JJ1 | The structure of F1-ATPase inhibited by piceatannol. | x-ray diffraction | A, B, C, H, I, J | — | — |
| 2JJ2 | The Structure of F1-ATPase inhibited by quercetin. | x-ray diffraction | A, B, C, H, I, J | — | — |
| 2JJ2 | The structure of F1-ATPase inhibited by quercetin. | x-ray diffraction | A, B, C, H, I, J | — | — |
| 2JMX | OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase | solution nmr | B | — | — |
| 2JMX | Oscp-nt (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase | solution nmr | B | — | — |
| 2W6E | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration:hydration… | x-ray diffraction | A, B, C | — | — |
| 2W6E | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6F | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6F | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6G | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6G | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6H | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6H | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6I | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6I | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6J | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2W6J | Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration… | x-ray diffraction | A, B, C | — | — |
| 2WSS | The structure of the membrane extrinsic region of bovine ATP synthase | x-ray diffraction | A, B, C, J, K, L | — | — |
| 2WSS | The structure of the membrane extrinsic region of bovine ATP synthase | x-ray diffraction | A, B, C, J, K, L | — | — |
| 2XND | Crystal structure of bovine F1-c8 sub-complex of ATP Synthase | x-ray diffraction | A, B, C | — | — |
| 2XND | Crystal structure of bovine F1-C8 sub-complex of ATP synthase | x-ray diffraction | A, B, C | — | — |
| 4ASU | F1-ATPase in which all three catalytic sites contain bound nucleotide, with magnesium ion released… | x-ray diffraction | A, B, C | — | — |
| 4ASU | F1-ATPase in which all three catalytic sites contain bound nucleotide, with magnesium ion released… | x-ray diffraction | A, B, C | — | — |
| 4TSF | The Pathway of Binding of the Intrinsically Disordered Mitochondrial Inhibitor Protein to F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 4TSF | The pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 4TT3 | The Pathway of Binding of the Intrinsically Disordered Mitochondrial Inhibitor Protein to F1-ATPase | x-ray diffraction | A, B, C | — | — |
| 4TT3 | The pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase | x-ray diffraction | A, B, C | — | — |
32 records more on the page itself.
Ligands
Experiment against prediction
- 6Z1R chain A against the predicted model P19483: TM-score 0.99, RMSD 0.78 Å
- 7AJI chain AA against the predicted model P19483: TM-score 0.99, RMSD 0.79 Å
- 6ZQM chain A against the predicted model P19483: TM-score 0.99, RMSD 0.79 Å
- 7AJG chain A against the predicted model P19483: TM-score 0.99, RMSD 0.79 Å
- 6ZPO chain A against the predicted model P19483: TM-score 0.99, RMSD 0.82 Å
- 6YY0 chain A against the predicted model P19483: TM-score 0.99, RMSD 0.82 Å
- 4ASU chain C against the predicted model P19483: TM-score 0.99, RMSD 0.84 Å
- 4ASU chain C against the predicted model P19483: TM-score 0.99, RMSD 0.84 Å
- 2JDI chain C against the predicted model P19483: TM-score 0.99, RMSD 0.87 Å
- 2JDI chain C against the predicted model P19483: TM-score 0.99, RMSD 0.87 Å
Elsewhere
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