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The crystallographic structure of restriction endonuclease eco ri at 3.3 a in the absense of DNA

Analyse The crystallographic structure of restriction endonuclease eco ri at 3.3 a in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1QC9
Type: protein
Length: 759 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (eco ri endonuclease)
EC: 3.1.21.4
UniProt: P00642
Pockets: 6 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Protein (eco ri endonuclease) (EC 3.1.21.4)	protein	253	33% helix, 17% strand	P00642

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.38	0.76	15	empty
2	92	0.36	0.75	17	empty
3	71	0.34	0.76	21	empty
4	77	0.33	0.74	16	empty
5	71	0.33	0.75	20	empty

Compared structures

1QC9 · The crystallographic structure of restriction endonuclease eco ri at 3.3 a in the absense… · the same entry in another collection · chain A against A, TM-score 1.00
P00642 · AlphaFold monomer V2.0 prediction for type-2 restriction enzyme ecori (P00642) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00642
Elsewhere: RCSB PDB 1QC9 · PDBe 1QC9 · UniProt P00642

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