UniProt P00642
Protein (eco ri endonuclease) (P00642)
Protein (eco ri endonuclease) (UniProt P00642), EC 3.1.21.4: 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P00642
- Protein
- Protein (eco ri endonuclease)
- EC
- 3.1.21.4
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 24 · 0 records with a druggable one
Structures
17 records of P00642 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CKQ | Pre-transition state eco ri ENDONUCLEASE/COGNATE DNA (tcgcgaattcgcg) complex | x-ray diffraction | A | — | 3 (best 0.38) |
| 1CKQ | Pre-transition state eco ri ENDONUCLEASE/COGNATE DNA (tcgcgaattcgcg) complex | x-ray diffraction | A | — | — |
| 1CL8 | A pre-transition state eco ri ENDONUCLEASE/COGNATE DNA (tcgcgapttcgcg) complex with DNA base analog… | x-ray diffraction | A | — | 3 (best 0.39) |
| 1CL8 | A pre-transition state eco ri ENDONUCLEASE/COGNATE DNA (tcgcgapttcgcg) complex with DNA base analog… | x-ray diffraction | A | — | — |
| 1ERI | X-ray structure of the DNA-eco ri endonuclease-DNA recognition complex: the recognition network and… | x-ray diffraction | A | — | 3 (best 0.39) |
| 1ERI | X-ray structure of the DNA-eco ri endonuclease-DNA recognition complex: the recognition network and… | x-ray diffraction | A | — | — |
| 1QC9 | The crystallographic structure of restriction endonuclease eco ri at 3.3 a in the absense of DNA | x-ray diffraction | A, B, C | — | 6 (best 0.38) |
| 1QC9 | The crystallographic structure of restriction endonuclease eco ri at 3.3 a in the absense of DNA | x-ray diffraction | A, B, C | — | — |
| 1QPS | The crystal structure of a post-reactive cognate DNA-eco ri complex at 2.50 a in the presence of… | x-ray diffraction | A | MN | 2 (best 0.35) |
| 1QPS | The crystal structure of a post-reactive cognate DNA-eco ri complex at 2.50 a in the presence of… | x-ray diffraction | A | — | — |
| 1QRH | X-ray structure of the DNA-eco ri endonuclease complexes with an R145K mutation at 2.7 a | x-ray diffraction | A | — | 2 (best 0.43) |
| 1QRH | X-ray structure of the DNA-eco ri endonuclease complexes with an R145K mutation at 2.7 a | x-ray diffraction | A | — | — |
| 1QRI | X-ray structure of the DNA-eco ri endonuclease complexes with an E144D mutation at 2.7 a | x-ray diffraction | A | — | 3 (best 0.41) |
| 1QRI | X-ray structure of the DNA-eco ri endonuclease complexes with an E144D mutation at 2.7 a | x-ray diffraction | A | — | — |
| 2OXV | Structure of the A138T promiscuous mutant of the EcoRI restriction endonuclease bound to its… | x-ray diffraction | A | — | — |
| 2OXV | Structure of the A138T promiscuous mutant of the ecori restriction endonuclease bound to its… | x-ray diffraction | A | — | — |
| P00642 | AlphaFold monomer V2.0 prediction for type-2 restriction enzyme ecori (P00642) | predicted | A | — | 2 (best 0.39) |
Ligands
- MN · Manganese (II) ion · in 1 record
Experiment against prediction
- 2OXV chain A against the predicted model P00642: TM-score 0.99, RMSD 0.61 Å
- 2OXV chain A against the predicted model P00642: TM-score 0.99, RMSD 0.61 Å
- 1QRI chain A against the predicted model P00642: TM-score 0.99, RMSD 0.49 Å
- 1QRI chain A against the predicted model P00642: TM-score 0.99, RMSD 0.49 Å
- 1ERI chain A against the predicted model P00642: TM-score 0.99, RMSD 0.56 Å
- 1ERI chain A against the predicted model P00642: TM-score 0.99, RMSD 0.56 Å
- 1QRH chain A against the predicted model P00642: TM-score 0.99, RMSD 0.55 Å
- 1QRH chain A against the predicted model P00642: TM-score 0.99, RMSD 0.55 Å
- 1QPS chain A against the predicted model P00642: TM-score 0.99, RMSD 0.64 Å
- 1QPS chain A against the predicted model P00642: TM-score 0.99, RMSD 0.64 Å
Elsewhere
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