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Crystal structure of the lactate dehydrogenase of cyanobacterium aponinum in its apo form.

Analyse Crystal structure of the lactate dehydrogenase of cyanobacterium aponinum in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 8AB2
Type: protein
Length: 329 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-lactate dehydrogenase
EC: 1.1.1.27
UniProt: K9Z684
Ligands: 7MT, TB
Pockets: 2 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	L-lactate dehydrogenase (EC 1.1.1.27)	protein	329	46% helix, 18% strand	K9Z684

Ligands and binding sites

7MT · Tb-Xo4 · ligand · chains A
TB · Terbium(iii) ion · metal · 3 copies · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	315	0.59	0.77	53	empty
2	120	0.51	0.80	19	empty

Compared structures

8AB2 · Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in its apo form. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K9Z684
Elsewhere: RCSB PDB 8AB2 · PDBe 8AB2 · UniProt K9Z684

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