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Catalytic domain of udp-glucose glycoprotein glucosyltransferase from chaetomium thermophilum (apo form)

Analyse Catalytic domain of udp-glucose glycoprotein glucosyltransferase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7ZKC
Type
protein
Length
278 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Udp-glucose-glycoprotein glucosyltransferase-like protein
UniProt
G0SB58
Ligands
NAG, CA
Pockets
2 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AUdp-glucose-glycoprotein glucosyltransferase-like proteinprotein27846% helix, 15% strandG0SB58

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
  • CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12610.610.8029empty
2900.350.7514empty

Modifications

Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

  • 7ZKC · Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium… · the same entry in another collection · chain A against A, TM-score 1.00

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