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Solution structure of human adenylate kinase 1 (HAK1)

Analyse Solution structure of human adenylate kinase 1 (HAK1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7X7S
Type
protein
Length
194 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Adenylate kinase isoenzyme 1
EC
2.7.4.3, 2.7.4.6
UniProt
P00568
Pockets
1 · best druggability 0.65

Structure

solution nmr · 1 distinct chain · 53% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAdenylate kinase isoenzyme 1 (EC 2.7.4.3, 2.7.4.6)protein19453% helix, 14% strandP00568

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13700.650.7952empty

Compared structures

  • 7X7S · Solution structure of human adenylate kinase 1 (hAK1) · the same entry in another collection · chain A against A, TM-score 1.00
  • P00568 · AlphaFold monomer V2.0 prediction for adenylate kinase isoenzyme 1 (P00568) · a predicted model of the same protein · chain A against A, TM-score 0.75

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